EUROPAD Journal on Addiction

EUROPAD Journal on Addiction


Heroin Addiction and Related Clinical Problems, the official journal of EUROPAD (European Opiate Addiction Treatment Association), is a peer-reviewed publication for professionals wanting to stay informed of research and opinion on opioid misuse treatment in Europe and around the world. A particular emphasis is on medication-assisted treatments for opioid addiction. Many articles consider the interface of pain and addiction. Full copies of the journal, dating back to its inception in 1999, are available here for free download as PDF documents. These are listed in descending order with the most current year and editions at the top.


2012   2011   2010   2009   2008    2007    2006    2005    2004    2003
2002    2001    2000    1999




Heroin Addiction and Related Clinical Problems. 2012(September), Vol. 14, No. 3

  • Assessing the current state of opioid-dependence treatment across Europe: methodology
    of the European Quality Audit of Opioid Treatment (EQUATOR) project.
  • Is substance use disorder with comorbid adult attention deficit hyperactivity disorder
    and bipolar disorder a distinct clinical phenotype?
  • Economic evaluation of opioid substitution treatment in Greece.
  • The journey into injecting heroin use.
  • Cognitive behavioural coping skills therapy in cocaine using methadone maintained
    patients: a pilot randomised controlled trial.

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Heroin Addiction and Related Clinical Problems. 2012(June), Vol. 14, No. 2

  • Ethnicity and drug addiction history. A comparison between Italian and Slovenian heroin addicts.
  • The Opiate Treatment Index (OTI) clinical interview: New evidence of its reliability and validity.
  • The effects of psychopathology and personality on substance abuse in twelve-step treatment programme abstainers, opiate substance abusers and a control sample.
  • Maladaptive behaviours after catastrophic events: the contribute of a “spectrum” approach to post traumatic stress disorders.
  • Reduction of psychotic symptoms during the use of exogenous opiates.
  • Clinical and social aspects of the illegal activities of people with psychoactive substance dependence in Russia.

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Heroin Addiction and Related Clinical Problems. 2012(March), Vol. 14, No. 1

  • How should methadone and buprenorphine treatment be organized and regulated?
  • Heroin addicts’ psychopathological subtypes. Correlations with the natural history of illness.
  • Profile of an addict, or, beyond the addiction mask.
  • Factors associated with discharge against medical advice from an alcohol and drug inpatient detoxification unit.
  • A compartmental model for the pharmacokinetics of heroin and its metabolites in man.
  • The state of the art regarding heroin addicts in prisons in Slovenia during the period from 1990 to 2008.
  • Clinical assessment of opiate induction: The Opiate Dosage Adequacy Scale Induction Form (ODAS-IF).

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Heroin Addiction and Related Clinical Problems. 2011(December), Vol. 13, No. 4

  • Self-reported differences in side-effects for 110 heroin addicts during opioid addiction and during methadone treatment.
  • Latent suicidality in heroin addicts.
  • Patients who use alcohol during MMT receive lower doses of methadone, show fewer positive urine analyses for opioids, and suffer from PTSD more frequently.
  • Further evidence of no relationship between anxiety-depressive mental status and dual diagnosis in heroin addicts entering treatment.
  • Requiring stabilized heroin addicts to stop successful agonist opioid treatment before liver transplantation can shift patients over to a cross-acting (alcohol) substance abuse.
  • Suboxone® switch data: A regional experience.
  • What concept of ‘spectrum’ is useful in addiction medicine?

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Heroin Addiction and Related Clinical Problems. 2011(September), Vol. 13, No. 3

  • Therapeutic management and comorbidities in opiate-dependent patients undergoing a replacement therapy programme in Spain: the PROTEUS study
  • Life events (loss and traumatic) and emotional responses to them in heroin-dependent patients before and after the dependence age of onset
  • A comparison of the drug use patterns, measures of needs and quality of life of methadone-maintained patients using and not using cocaine
  • Sociodemographic and clinical differences among deceased and surviving cohort members of opioid maintenance therapy

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Heroin Addiction and Related Clinical Problems. 2011(June), Vol. 13, No. 2

SPECIAL EDITION: Basics of Addiction
A Training Manual for Medical Practitioners on Opioid Dependence

  • Introduction
  • Neurobiology of Opioid Dependence
  • Clinical Assessment of Opioid Dependence
  • Maintenance Pharmacotherapies: Treatment Principles and Clinical Application
  • Conclusions

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Heroin Addiction and Related Clinical Problems. 2011(March), Vol. 13, No. 1

  • Tobacco smoking prevalence in a large sample of heroin users accessing rehabilitation
  • Housing and employment situation, body mass index and dietary habits of heroin addicts
    in methadone maintenance treatment
  • Effect of valproate on benzodiazepine withdrawal severity in opioid-dependent subjects
  • Opioid addiction complicated by alcoholism (in young men)
  • Dual Diagnosis (Comorbidity): A growing diagnostic and treatment issue in psychiatric
    and substance use programmes
  • Does cannabis have therapeutic benefits for withdrawing opioid addicts?
  • Is it time for new studies on the level of insight in heroin addicts to promote compliance
    with methadone treatment?

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Heroin Addiction and Related Clinical Problems. 2010(December), Vol. 12, No. 4

  • Psychiatric Comorbidity in Substitution Treatment of Opioid-Dependent Patients in Primary
    Care: Prevalence and Impact on Clinical Features
  • Methadone Maintenance Therapy and Feto-Maternal Outcomes of Pregnancy
  • On Opioid Receptors
  • Psychotherapeutic Management of Heroin-Addicted Patients: Psychopathological, Relational
    and Organizing Aspects
  • Treating Heroin Addicts: Blocking Dosages and Stimulation-Stabilization of Opioidergic System
  • Is it Time for a Responsible Administration of Gamma Hydroxybutyrate and Methadone?
  • Opiate Maintenance Treatment in Primary Health Care in Germany


Heroin Addiction and Related Clinical Problems. 2010(September), Vol. 12, No. 3

  • Psychological performance and sedation following injectable opioid administration
  • Treatment practices and perceived challenges for European physicians treating opioid dependence
  • Clinical foundations for the use of methadone in patients with infectious diseases
  • Bioethical preferences of supporters and opponents of agonist opioid therapy in Russia
  • The pleasure constant


Heroin Addiction and Related Clinical Problems. 2010(June), Vol. 12, No. 2

  • Addiction: Challenging the Dual Diagnosis Construct
  • Adherence and Social Antecedents in Relation to Outcome in Methadone Maintenance Treatment (MMT)
  • Additional Take-Home Dosages
  • From Methadone to Buprenorphine or Back to Methadone. The Croatian Experience
  • Methadone Treatment for Pregnant Heroin Addicted Women
  • What is the Right Dosage for Our Patients?


Heroin Addiction and Related Clinical Problems. 2010(March), Vol. 12, No. 1

  • Evaluation of Opioid-Dependent Prisoners in Oral Opioid Maintenance Therapy
  • Dose Determination in Dual Diagnosed Heroin Addicts during Methadone Treatment
  • Urine Labelling Marker System for Drug Testing Improves Patient Compliance
  • Quality of Life as a Means of Assessing Outcome in Opioid Dependence Treatment
  • Why There Has Been an Excess of Overdoses in Norway Since 1990?

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Heroin Addiction and Related Clinical Problems. 2009(December), Vol. 11, No. 4

  • QT Interval
  • Psychoactive Drugs and Prolongation of the QT Interval
  • Opioid Treatment and “Long-QT Syndrome (LQTS)”: a Critical Review of the Literature
  • Management of Cardiac Risk during Methadone Treatment: Focus on the QT Interval
  • Cardiovascular Complications of Cocaine Use


Heroin Addiction and Related Clinical Problems. 2009(September), Vol. 11, No. 3

  • Methadone Treatment in Italy in the Third Millennium: Continuing Fear of Treatment
  • Pharmacology and Neurochemistry of Methadone
  • Cannabis and Premonitory Symptoms of Schizophrenia: What Is the Time Sequence?
  • Alcoholics With a History of Heroin Consumption: Clinical Features and Chronology of Substance Abuse
  • Opioid Dependence and Quality of Life: Changes in the Heroin Epidemic
  • Predictors for Non-Relapsing in Methadone- and Buprenorphine-maintained Heroin Addicts: A Comparative Study
  • Echoing the Patient’s Lack of Insight: A Role We Must Avoid Playing


Heroin Addiction and Related Clinical Problems. 2009(June), Vol. 11, No. 2

  • QTc Interval Screening. American Association for the Treatment of Opioid Dependance (AATOD) Policy and Guidance Statement
  • New Approaches in the Treatment of Opioid Dependency During the Pregnancy
  • Substitution Therapy. A New Problem of Biomedical Ethics and Medical Law
  • Methadone-treated Patients After Switching to Buprenorphine in Residential Therapeutic Communities: An Addiction-specific Assessment of Quality of Life
  • Clinical Trial on the Use of Olanzapine in Reducing the Consumption of Cocaine in Methadone Maintenance Programmes
  • Voices of Experience: Attitudes and Opinions of Recipients of Unsupervised Injectable Opiate Treatment in the Northwest of England
  • Swedish Use and Misuse of the Dole & Nyswander Treatment


Heroin Addiction and Related Clinical Problems. 2009(March), Vol. 11, No. 1

  • Treatment of Opioid Dependence and ADHD/ADD with Opioid Maintenance and Central Stimulants
  • Dihydrocodeine for the Treatment of Alcohol Dependence
  • Use and Abuse of High-Dose Buprenorphine (HDB) Obtained Without a Prescription
  • A 10-Year Evaluation of Chronic Pain Patients Treated with Opioids
  • Psychotherapeutic Experiences with Methadone Maintained Patients in the Framework of Multidisciplinary Clinical Institution
  • Preferences for Buprenorphine/Naloxone (Suboxone®) and Buprenorphine (Subutex®) in Patients Receiving Buprenorphine Maintenance Therapy in France: A Prospective, Multicentre Study
  • Coordinating Methadone Treatment Providers and Policymakers: Lessons Learned Over 30 Years
  • En Route to 90% Retention. ‘Active Rehabilitation’ in Central Norway

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Heroin Addiction and Related Clinical Problems. 2008(December), Vol. 10, No. 4

  • Buprenorphine-Naloxone Versus Methadone Maintenance Therapy: A Randomized Double-Blind Trial with Opioid-Dependent Patients
  • Predictors for Non-Relapsing Status in Methadone Maintained Heroin Addicts. A Long Term Prospective Study
  • Unintentional and Intentional Injuries Due to Opiate Abuse
  • Scientific Evidence and Practical Experience with Methadone-Assisted Withdrawal of Heroin-Dependent Pregnant Patients
  • Opioid Therapy and Restoration of the Immune Function in Heroin-Addicted Patients
  • Major Policy and Clinical Developments in the Use of Methadone and Buprenorphine Treatment in the US


Heroin Addiction and Related Clinical Problems. 2008(September), Vol. 10, No. 3

  • The Under Treatment of Pain: A Global Problem. An Educational Approach
  • Pseudo-Addiction: The Illustrative Case of Howard Hughes
  • When a New Drug Promotes the Integration of Treatment Modalities: Suboxone and Harm Reduction
  • Finnish Experience With Buprenorphine-Naloxone Combination (Suboxone®): Survey Evaluations With Intravenous Drug Users
  • Fifteen Years of Office-Based Prescribing in Croatia. Attitudes, Obstacles, and Outcomes


Heroin Addiction and Related Clinical Problems. 2008(June), Vol. 10, No. 2

  • Evaluation of Therapeutic Alternatives to Imprisonment for Drug-Dependent Offenders
  • Motivational Interventions for Methadone-Treated Patients
  • Health Care Utilization and Morbidity Associated With Methadone and Buprenorphine Treatment
  • Office-Based Methadone Maintenance Treatment: Therapeutic Efficacy and Predictors of Clinical Response
  • Use of Sertraline in Depressed Methadone Maintenance Patients
  • Download PDF: HeroinAdd10-2.pdf (1.28 MB, 44 pp)


Heroin Addiction and Related Clinical Problems. 2008(March), Vol. 10, No. 1

  • Sexual Behaviour of Heroin Addicts in Treatment
  • First Experience of Opioid Therapy with Buprenorphine in Ukraine
  • Administration of Nalbuphine to Heroin Addicts. Feasibility and Short-Term Effects
  • Evidence of Reliability and Validity of the Opiate Dosage Adequacy Scale (ODAS) in a Sample of Methadone Maintenance Patients
  • Improvement in the Quality of Live in Heroin Addicts: Differences Between Methadone and Buprenorphine Treatment
  • Methadone: A Fast and Powerful Anti-anxiety, Anti-depressant and Anti-psychotic Treatment
  • Explaining Agonist Treatment Through Movie Language: The Interesting Allegory of ‘Videodrome’
  • Download PDF: HeroinAdd10-1.pdf (2.77 MB, 60 pp) Large File

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Heroin Addiction and Related Clinical Problems. 2007(December), Vol. 9, No. 4

  • Addiction Treatment: When Will Medical Principles Matter?
  • Maintenance: How Long?
  • Agonist Opioid Treatment in Prisons
  • The Need For Patient Education. Opinions And Attitudes On Heroin Addiction
  • Motivational Interviewing: Linking Systems and Dancing with Clients
  • Download PDF: HeroinAdd9-4.pdf (1.4 MB, 60 pp)


Heroin Addiction and Related Clinical Problems. 2007(September), Vol. 9, No. 3

  • Addiction Treatment: When Will Medical Principles Matter?
  • New Approaches in the Treatment of Opioid Dependency during Pregnancy
  • Clinical Features of Heroin Dependence Onset in Young Women
  • Supporting GP’s in Improving Substitute Prescribing for Opiate Users in the UK
  • Mortality Among Opiate Abusers in Stockholm: A Longitudinal Study
  • Methadone Treatment in an Italian Criminal Mental Hospital


Heroin Addiction and Related Clinical Problems. 2007(June), Vol. 9, No. 2

  • Can Heroin Maintenance Treatment Be Called a Therapy?
  • Brain Disintegration in Heroin Addicts: The Natural Course of the Disease and the Effects of Methadone Treatment
  • Voucher-Based Reinforcement Therapy for Drug-Dependent Pregnant Women
  • Pharmacokinetic and Pharmacogenetic Factors Influencing Methadone Plasma Levels
  • Providing Comprehensive Treatment in Medication Assisted Opioid Treatment: The Development of Needs Based Treatment at a Medical School Sponsored Program
  • Dihydrocodeine Treatment of Alcohol Addicts With Previous Opiate Addiction — Case Reports


Heroin Addiction and Related Clinical Problems. 2007(March), Vol. 9, No. 1

  • Effects of Opioid Pharmacotherapy on Psychomotor and Cognitive Performance: A Review of Human Laboratory Studies of Methadone and Buprenorphine
  • The Vincent P. Dole Research and Treatment Institute for Opiate Dependence: An Integrated Biopsychosocial Model for the Treatment of Methadone Maintained Patients
  • Opioid Substitution with Methadone and Buprenorphine: Sexual Dysfunction as a Side Effect of Therapy
  • Paxil (Paroxetine) in Complex Therapy in Heroin Addicts
  • Use of Sodium Gamma-Hydroxybutyrate (GHB) in Alcoholic Heroin Addicts and Polydrug-Abusers
  • Download PDF:  HeroinAdd9-1.pdf  (1.57 MB, 84 pp)

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Heroin Addiction and Related Clinical Problems. 2006(Dec), Vol. 8, No. 4

  • Combating the Stigma: Discarding the Label “Substitution Treatment”
    in Favour of “Behaviour-Normalization Treatment”
  • In the Service of Patients: The Legacy of Dr. Dole
  • Injecting Buprenorphine Tablets: A Manageable Risk
  • QTc Prolongation in Methadone Maintenance: Fact and Fiction
  • Methadone: Is It Enough?
  • Download PDF:  HeroinAdd8-4.pdf  (1.05 MB, 68 pp)


Heroin Addiction and Related Clinical Problems. 2006(Sept), Vol. 8, No. 3

  • In Memory of Vincent P. Dole
  • Forty Years of Methadone Maintenance Treatment Around the World; Past, Present and Future
  • Methadone and Treatment Quality. The EFQM Excellence Model
  • Treatment of Chronic Hepatitis C Virus Infection in Intravenous Drug Addicts: State of the Art
  • Download PDF:  HeroinAdd8-3.pdf  (983 KB, 52 pp)

Heroin Addiction and Related Clinical Problems
. 2006(June), Vol. 8, No. 2

  • Say “Yes” to Methadone and Buprenorphine in Russian Federation
  • Knowledge and Attitudes of Drug Treatment Professionals Toward HIV Prevention and Care Activities in the Russian Federation
  • A Low-Value Voucher Contingency Management Programme with Israeli Methadone-Maintained Patients – A Pilot Evaluation Study
  • Treatment for Hepatitis C in Jail Houses is Doable and Successful: Definitive Data of First National French Study (POPHEC)
  • Is Heroin Addiction Related to a Dysfunctional Processing of Reward and Hedonism in the Brain? Insights from Neuroimaging Studies
  • Download PDF:  HeroinAdd8-2.pdf  (970 KB, 60 pp)

Heroin Addiction and Related Clinical Problems. 2006(March), Vol. 8, No. 1

  • Necessity of a World Federation of Health Organizations Providing Opiate Agonist Therapy for Heroin Addicts
  • Heroin Dependence in the Russian Federation: The Current Situation
  • No Intrauterine Growth Retardation in Babies of Mothers Stabilized on Methadone Before Conception and Throughout Their Pregnancies
  • Effectiveness of Buprenorphine in Double Diagnosed Patients. Buprenorphine as a Psychotropic Drug
  • Download PDF:  HeroinAdd8-1.pdf  (918 KB, 52 pp)

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Heroin Addiction and Related Clinical Problems. 2005(Dec), Vol. 7, No. 4

  • Addiction and Pregnancy
  • Primary Care Physicians and Addiction Treatment in Germany. Decentralization and Take-home Policy
  • Psychopathological Disorders in Heroin Addicts and Administration of Risperidone During Rehabilitation
  • Methadone Reduces the Need for Antipsychotic and Antimanic Agents in Heroin Addicts Hospitalized for Manic and/or Acute Psychotic Episodes
  • Methadone Serum Concentration and its Relationship to Methadone Dose Revisited
  • Medical and Social Factors Determining Early Poly-Drug Dependence
  • Download PDF:  HeroinAdd7-4.pdf  (1.20 MB, 70 pp)

Heroin Addiction and Related Clinical Problems
. 2005(Sept), Vol. 7, No. 3

  • Psychotherapy for Patients in Methadone Treatment
  • Buprenorphine High-Dose, Broad Spectrum, Long-term Treatment: A New Clinical Approach to Opiate Alkaloid Dependency
  • Correlation Between High Methadone Dose and Methadone Blood Levels in Methadone Maintenance Treatment Patients
  • Addictive Disorders, Bipolar Spectrum, and the Impulsive Link: The Psychopathology of a Self-Regenerating Pathway
  • Bridging the Preclinical-Clinical Gap
  • Mortality and Retention of Drug Users in GP Shared Care in Glasgow
  • Working with the Patient for Optimal Treatment Outcomes in UK General Practice
  • Download PDF:  HeroinAdd7-3.pdf  (1.00 MB, 60 pp)

Heroin Addiction and Related Clinical Problems
. 2005(June), Vol. 7, No. 2

  • Methadone Maintenance Treatment and Mood Disturbances: Pharmacological and Psychological Implications
  • Long-term Treatment for Patients with Severe Mental Illness and Substance Abuse
  • Good Practice, Good Results. Maintenance Treatment Outcomes in France
  • The Endogenous Cannabinoid System: Physiological Modulation of Neuronal Activity
  • Substitution Treatment in European Prisons. A Study of Policies and Practices of Substitution Treatment in Prison in 18 European Countries
  • Medical Meaning of Psychosocial Issues of Heroin Addiction
  • Download PDF: HeroinAdd7-2.pdf  (1.13 MB, 52 pp)

Heroin Addiction and Related Clinical Problems
. 2005(March), Vol. 7, No. 1

  • Europad 6th Conference, Paris, France, EU
  • Buprenorphine Induction and Stabilisation in the Treatment of Opiate Dependence
  • Clinical Significance of Electroencephalographic Abnormalities in Heroin Addicts: Systematic Review
  • Alcohol Abuse in Heroin Addicts: An Unfolding Metabolic Destiny
  • Symptomatic Treatment of Opiate Withdrawal Syndrome by Low-dose Buprenorphine in an In-Patient Setting
  • Open Letter to Physicians and Other Health Care Providers Facing Pain Management During Opioid Agonist Therapy with Methadone
  • Download PDF:  HeroinAdd7-1.pdf  (967 KB, 52 pp)

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Heroin Addiction and Related Clinical Problems. 2004(Dec), Vol. 6, No. 3

  • Patient-Treatment Matching and Opioid Addicted Patients: Past Methods and Future Opportunities
  • Methadone Patients’ Sexual Dysfunctions: Clinical and Treatment Issues
  • Unreported Double Frequency of Heroin Addicts Visiting Psychiatric Services and Addiction Treatment Services
  • Evaluation of Effectiveness of Drug Treatment Programmes in the Ukraine
  • Bad Patients or Bad Treatment?
  • Opiate Dosage Adequacy Scale (ODAS): A Clinical Diagnostic Tool as a Guide to Dosing Decisions
  • Download PDF:  HeroinAdd6-3.pdf  (1.20 MB, 54 pp)

Heroin Addiction and Related Clinical Problems
. 2004(August), Vol. 6, No. 2

  • Craving in Opiate, Cocaine and Alcohol Addiction
  • Clinical Foundations for the Use of Methadone in Jail
  • Download PDF:  HeroinAdd6-2.pdf  (2.24 MB, 78 pp)

Heroin Addiction and Related Clinical Problems. 
2004(April), Vol. 6, No. 1

  • Addressing Violence in Methadone Maintenance Treatment
  • “Vedette” Study and “Tracking” Project; Their Integration and Preliminary Results
  • Methadone Treatment. Safe Induction Techniques
  • Naltrexone as Maintenance Therapy for Heroin Addiction: Predictors of Response
  • Download PDF:  HeroinAdd6-1.pdf  (1.65 MB, 60 pp)

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Heroin Addiction and Related Clinical Problems. 2003(Dec), Vol. 5, No. 3

  • Understanding the Pathogenesis of Drug Addiction in Order to Implement a Correct Pharmacological Intervention
  • Structured Motivational Interventions in Methadone Maintenance Treatment
  • Psychiatric Severity and Treatment Response in Methadone Maintenance Treatment Programmes: New Evidence
  • Treatment of Prisoners Addicted to Prohibited Drugs in Institutions for Criminal Law Sanctions in Maribor, Slovenia
  • -Clinical Picture and Treatment of Psycho-organic Syndrome in Drug Addicts
  • Download PDF:  HeroinAdd5-3.pdf  (1.97 MB, 60 pp)

Heroin Addiction and Related Clinical Problems
. 2003(August), Vol. 5, No. 2

  • Dual Diagnosis in Heroin Addicts. The Clinical and Therapeutic Aspects
  • Personality Disorders in Addicted Patients
  • Mood Disorders in Addicted Patients
  • Anxiety Disorders in Addicted Patients
  • Aggression and Violence in Heroin Addicted Patients
  • Alcoholism in Heroin-Addicted Patients
  • Methadone Treatment in Dual Diagnosis Patients
  • Download PDF:  HeroinAdd5-2.pdf  (2.18 MB, 108 pp)

Heroin Addiction and Related Clinical Problems
. 2003(April), Vol. 5, No. 1

  • The Impact of Methadone Substitution Therapy (MST) on Illicit Drug Use and Drug Abuse-Related Quality of Life: A European Study
  • When “Enough” is Still Not “Enough”. Effectiveness of High-Dose Methadone in the Treatment of Heroin Addiction
  • The Impact of Continuing Terror and Stress on the Use of Psychoactive Drugs in Israel
  • Reduction in Self-Reported Nicotine Dependence After Stabilization in Methadone Maintenance Treatment
  • Liver Cytochrome Overexpression in Human HCV Infection
  • Download PDF:  HeroinAdd5-1.pdf  (1.42 MB, 52 pp)

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Heroin Addiction and Related Clinical Problems. 2002(Dec), Vol. 4, No. 3

  • Harm Reduction and Specific Treatments for Heroin Addiction. Different Approaches or Levels of Intervention? An Illness Centered Perspective
  • Methadone Treatment in Croatia
  • The Renaissance of Methadone Treatment in America
  • Methadone and Commonplaces
  • Methadone Maintenance and HIV Infection
  • Breast-Feeding for a Methadone-Maintained Mother: A Case Report
  • Methadone Maintenance Treatments in European Extra-Community Target
  • Download PDF:  HeroinAdd4-3.pdf  (1.36 MB, 52 pp)

Heroin Addiction and Related Clinical Problems
. 2002(August), Vol. 4, No. 2

  • Correlation Between Hepatitis C Serostatus and Methadone Dose Requirement in 1,163 Methadone-Maintained Patients
  • Is Craving for Heroin and Alcohol Related to Low Methadone Dosages in Methadone Maintained Patients?
  • Clinical Foundations for the Use of Methadone. Italian Consensus Panel on Methadone Treatment
  • “Manifesto of Barcelona”: Care Programmes for Health Professionals with Mental
  • Disorders and Addictive Behaviours in Europe
  • Galicia Document on Problems Related to Addictive Disorders in Europe
  • 5th Conference of The European Opiate Addiction Treatment Association and 2002 “Chimera Award”
  • Download PDF:  HeroinAdd4-2.pdf  (556 KB, 52 pp)

Heroin Addiction and Related Clinical Problems
. 2002(April), Vol. 4, No. 1

  • Mortality Among Problem Drug Users in Europe: A Project of the European Monitoring Centre for Drugs and Drug Addiction (EMCDD)
  • Buprenorphine: Evidence for Effectiveness
  • 1995-2001 Programme Evaluation of the A-Center for Treatment of Addicts Consuming Prohibited Drugs at Maribor, Slovenia
  • Does Therapeutic Threshold of Methadone Concentration in Plasma Exist?
  • Treatment Characteristics and Retention in Methadone Maintenance: High and Stable Retention Rates in a Swedish Two-Phase Programme
  • Download PDF:  HeroinAdd4-1.pdf  (448 KB, 50 pp)

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Heroin Addiction and Related Clinical Problems. 2001(Dec), Vol. 3, No. 2

  • The Problem of Drug Dependence
  • Evaluation Survey of a Methadone Treatment Share Care Programme Between a Specialized Clinic and a Network of GPs
  • Treatments of Substance Users Detainees in La Santé Prison
  • Intensive Sport and Risk of Heroin Addiction
  • The Differences Between Heroin Addicts With and Without Comorbidity
  • Methadone Treatment: Italy vs USA – Methadone Treatment in Europe
  • Download PDF:  HeroinAdd3-2.pdf  (1.52 MB, 52 pp)

Heroin Addiction and Related Clinical Problems
. 2001(June), Vol. 3, No. 1

  • The Promise of Opioid Receptor Antagonist Drugs in the Treatment of Neuropsychiatric Disorders
  • Haematic Concentrations Versus Oral Doses of Methadone. Comparative Assessment of Two Reference Systems During Substitute Therapy in Opiate Addiction
  • Therapeutic Effects of Paroxetine on the Cocaine Abuse in Heroin Addicts
  • Methadone Regulations in USA: Comments, Proposal to Adopt New Regulations and Proposed Rule
  • Articulation of Codeine Treatment and Methadone Maintenance Programs
  • The Differences Between Inpatients and Outpatients with Illegal Drug Use: Prevalence of Comorbid Mental Disorders
  • Download PDF: HeroinAdd3-1.pdf  (1.20 MB, 48 pp)

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Heroin Addiction and Related Clinical Problems. 2000(Dec), Vol. 2, No. 2

  • Managing Benzodiazepine Withdrawal
  • Addiction and Methadone: One American’s View
  • An Evaluation Study on Share Care Methadone Treatment Between a Specialized Clinic and a Network of General Practitioners
  • Opioids and Cannabinoids Abuse Among Bipolar Patients
  • Pregnant Addict Care in Methadone Treatment Programs
  • Prohibitionism, a Feasible Way Forward
  • Hepatitis C Infected Patients and Higher Doses of Methadone
  • Introducing the European Collaborating Centres in Addiction Studies (ECCAS)
  • Download PDF:  HeroinAdd2-2.pdf  (737 KB, 70 pp)

Heroin Addiction and Related Clinical Problems. 
2000(June), Vol. 2, No. 1

  • Women, Pregnancy and Methadone
  • Sexual Dysfunction Associated with Methadone Maintenance: Treatment with Bromocriptine
  • Attitudes and Beliefs Towards Methadone of Staff Working in Substance Abuse Treatment
  • Is Prescribing Higher Doses of Methadone Likely to Promote Elevated Drop-out Rates?
  • The Pacific Drug Policy Institute and Research Findings That Led to Its Founding
  •  Methadone Treatment: An Interesting Analogy
  • Take-Home Doses and Compliance with Methadone Maintenance Treatment
  • Methadone Dose and Retention in Treatment of Heroin Addicts with Bipolar I Disorder Comorbidity, Preliminary Results
  • Discontinuation Symptoms are Not Addiction/Dependence
  • Download PDF:  HeroinAdd2-1.pdf  (545 KB, 60 pp)

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Heroin Addiction and Related Clinical Problems. 1999(Dec), Vol. 1, No. 2

  • Alcohol, Benzodiazepines and Other Drug Use in Heroin Addicts Treated with Methadone. Polyabuse or Undermedication?
  • What Defines Switzerland’s Drug Policy? Switzerland: Drug Policy of Mountain Dwellers?
  • Methadone Treatment and Spread of AIDS in Europe in the 1987-1992 Years
  • Adolescent Narcotism in Russia
  • The Treatment of Viral Hepatitis in Drug Addicts
  • General Practitioners and Heroin Addiction. Chronicle of a Medical Practice
  • Download PDF:  HeroinAdd1-2.pdf  (290 KB, 46 pp)

Heroin Addiction and Related Clinical Problems
. 1999(June), Vol. 1, No. 1

  • Treating Heroin Addicts, i.e. “Breaking through a Wall of Prejudices”
  • Heroin Addiction as Normal Illness
  • Methadone Maintenance Comes of Age
  • Pharmacokinetics and Pharmacogenetics of Methadone: Clinical Relevance
  • Integrating Methadone Treatment in the Slovenian Public Health System
  • Treatment of Opiate Dependency: A Comment
  • Methadone as a Mood Stabilizer
  • Download PDF:  HeroinAdd1-1.pdf  (338 KB, 54 pp)

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