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The mission of Pain Treatment Topics is to serve as a noncommercial resource for healthcare professionals, providing open access to clinical news, information, research, and education for a better understanding of evidence-based pain-management practices. Advertising is not accepted.
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July-August 2008 News/Research UPDATES
 In this latest edition >>
> A Bonus of Opioid Therapy: Psychotherapeutic Effects
> IV Morphine Titration Relieves Acute Pain in the ED
> Guidelines for Parental Methadone in Palliative Care
> Rotation From Other Opioids to Methadone Reviewed
> Whiplash Injury Trigger Points Identified
> Improved Coping Skills Help Headache Sufferers
> Yoga Helps Improve Low Back Pain, Flexibility
> Drug Combo Increases Remission in Early RA
> Pot Provides Neuropathic Pain Relief, Study Says
> Recent Drug or Device Approvals and Announcements
And, much more... See News/Research Updates...>
NEW Current Comments - Opioid Concerns
The OIH Paradox: Can Opioids Make Pain Worse?
By: Peggy Compton, RN, PhD, Pain Treatment Topics, August 2008.
 This evidence-based review examines how ongoing opioid therapy for chronic pain can paradoxically worsen the pain in some patients, a phenomenon called Opioid-Induced Hyperalgesia or OIH. The differential diagnosis of OIH from other conditions – worsening disease, opioid tolerance, withdrawal, pseudoaddiction, or addiction – is described and strategies for avoiding or managing OIH, if it occurs, are recommended. See Article...>
Vitamin D in PPM Journal
Vitamin D for Chronic Pain
By: Stewart B. Leavitt, MA, PhD. Practical Pain Management (PPM). 2008(Jul/Aug);8(6):24-42.
According to this 13-page evidence-based review of the clinical research, helping certain patients to overcome chronic musculoskeletal pain and fatigue syndromes may be as simple, well tolerated, and inexpensive as a daily supplement of vitamin D. This article is reprinted courtesy of the medical journal Practical Pain Management. Go to the Article...>
NEW Pain Disorders Section - PEDIATRICS
Infants and children can and do feel pain comparable to pain in adults. Research into pediatric pain has grown rapidly, and numerous drug and non-drug therapies have been developed and tested in a variety of clinical populations and settings. However, inadequate prevention and relief of pediatric pain are still widespread. Documents in this new section focus on the most appropriate, cost effective, and evidence-based interventions, taking into account all components of the child’s pain experience and comfort needs. Go to the New Section...>
CME Courses Updated/Expanded
This latest update under the Pain-Topics.org “Education/CME Locator” tab includes nearly 90 changes: 37 new CME's were added and 52 listings were reviewed & revised. Whether or not you are looking for CME/CEU credits, these offerings generally provide very current and concise discussions of vital topics in pain management. Go to CME Listings...>
PATIENT RESOURCES of Importance...
Healing Inspirations for Living with Pain
While modern medicine can do much to allay the physical experience of chronic pain conditions, certain dimensions of pain can be difficult to treat and may benefit from other approaches. Resources in this section recommend how patients can learn to calm down, get centered, and take their individual journeys in overcoming adversity one step and one day at a time. See Details...>
Vitamin D: A Champion of Pain Relief
Overcoming chronic pain may be as simple, safe, and inexpensive as an extra dose of vitamin D each day. This 6-page brochure explains in easy-to-understand language what vitamin D is and how it works. In also describes how inadequate vitamin D intake may play a role in aches and pains, as well as the benefits of vitamin D supplementation for relieving these symptoms. See Details...>
Recent Opioid Rx Papers of Interest…
The following overview papers provide important clinical information for all healthcare providers on the effective and safe use of opioid analgesics:
Opioid Pharmacology
By: Andrea M. Trescot, MD, et al. Pain Physician; 2008.
See details…>
Monitoring Opioid Adherence in Chronic Pain Patients:
Tools, Techniques, and Utility
By: Laxmaiah Manchikanti, MD, et al. Pain Physician; 2008.
See details…>
Guidelines/Reports Sections UPDATED
Quite a number of new additions and changes have been made under the Pain-Topics.org Guidelines/Reports tab.
As always, look for the “NEW” icon to see at-a-glance what items are new or have changed.
Position/Policy/Consensus Statements
11 new entries and 18 updates were made to this section. One new item focuses on "Opioids and the management of chronic severe pain in the elderly." Go to Section...>
Pain Treatment Guidelines
4 new guidelines were added. For example, one focuses on ACR 2008 recommendations for the use of non-biologic and biologic DMARD in rheumatoid arthritis. Another addresses opioids in the management of chronic non-cancer pain. Go to Section...>
Systematic Reviews
4 new reviews have been added. This section includes reviews pertaining to pain management from the Cochrane Database as well as from many other sources. Go to Section...>
Updated Methadone Safety Guidance
Methadone is a good choice for cancer pain and chronic noncancer pain, but special safety cautions must be observed as methadone's pharmacokinetics and pharmacodynamics are unique among opioids. These documents discuss the critical safety issues and provide guidance for methadone analgesia dosing, as well as special instructions for patients.
Access These Documents...>
Oral Methadone Dosing for Chronic Pain
By: James D. Toombs, MD; March 2008.
Methadone Safety Handout for Patients
By: Stewart B. Leavitt, MA, PhD; March 2008.
Keeping Patients Safe from Iatrogenic Methadone Overdoses
From: Institute for Safe Medication Practices (ISMP). February 14, 2008.
SPECIAL ANNOUNCEMENTS 
Using Opioids for Pain in Substance Abusing Patients
This excellent article from the National Institute on Drug Abuse (NIDA), by experts in the pain and addiction fields, discusses the neurobiology and clinical presentation of pain and its synergies with substance use disorders, presents methodical approaches to the evaluation and treatment of pain that co-occurs with substance abuse, and provides practical guidelines for the use of opioids to treat pain in individuals with histories of addiction.
<See Details & Download Article>
Free Newsletters Focus on Pain Management
Currents: Pain Management News & Research is the free monthly newsletter from the American Academy of Pain Management (AAPM). Each month, researchers and editorial staff at AAPM review more than 20,000 news stories, journal abstracts, and other resources to find those that are most relevant to pain management practitioners. AAPM membership is not required to subscribe. <See Details & Subscribing Info>
Pain Relief Connection is a monthly e-mailed newsletter from the Massachusetts General Hospital (MGH) Cares About Pain program. It alerts readers to important current news and resources in the pain management field, and is a great time-saver for practitioners wanting to know about developments in the field. <See Details & Subscribing Info>
New APF Report Addresses Opioid Analgesia Concerns
The American Pain Foundation (APF) released a new report outlining critical barriers to opioid prescribing for pain management, and calls for a more balanced consideration of the risks and benefits of these vital analgesics. A 16-page document summarizes key challenges and actionable solutions discussed by leading pain experts at a recent roundtable meeting.
<Download the Report>
The Pain Practitioner Special Edition - FIBROMYALGIA
This special issue of The Pain Practitioner journal focusing on fibromyalgia (FM) is designed to show exactly how real the syndrome is and how far it has come medically. An excellent compendium of 9 articles is authored by experts in the field. Topics include: advances in FM research, treatment options, treating comorbidities of FM, psychosocial aspects, and adopting integrative approaches that combine basics with innovative therapies.
<See Details and Download Journal >
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Stewart B. Leavitt, MA, PhD; Publisher & Editor-in-Chief
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