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Pain Treatment - Systematic Reviews
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CONTENTS
Acute Pain
Moore RA, Straube S, Wiffen PJ, Derry S, McQuay HJ. Cochrane Database. 2009, 3. Pregabalin has efficacy in neuropathic pain and fibromyalgia. A minority of patients will have substantial benefit, and more will have moderate benefit. Many will have little benefit or will discontinue because of adverse events. Individualized of treatment is needed to maximize pain relief. There is no evidence to support the use of pregabalin in acute pain. Accessed July 11, 2009. See abstract…> Lamotrigine for acute and chronic pain Wiffen PJ, Rees J. Cochrane Database. 2007,2. Accessed August 24, 2009. See abstract...> Piracetam for reducing the incidence of painful sickle cell disease crises Al Hajeri AA, Fedorowicz Z, Omran A, et al. Cochrane Database. 2007,2. Accessed August 24, 2009. See abstract...> Colchicine for acute gout Schlesinger N, Schumacher R, Catton M, et al. Cochrane Database. 2006,4. Accessed August 24, 2009. See abstract...> Music for pain relief Cepeda MS, Carr DB, Lau J, et al. Cochrane Database. 2006,2. Accessed August 24, 2009. See abstract...> Topical analgesia for acute otitis media Foxlee R, Johansson AC, Wejfalk J, et al. Cochrane Database. 2006,3. Accessed August 24, 2009. See abstract...> The symptom of pain with heart failure: a systematic review Godfrey C, Harrison MB, Medves J, et al. J Card Fail. 2006(May);12(4):307-313. Accessed February 27, 2009. See abstract...> Approach to undifferentiated chest pain in the emergency department: a review of recent medical literature and published practice guidelines Ringstrom E, Freedman J. Mt Sinai J Med. 2006(Mar);73(2):499-505. Accessed February 27, 2009. See PDF text...> Topical NSAIDs for acute pain: a meta-analysis Mason L, Moore RA, Edwards JE, et al. BMC Fam Pract. 2004(May);5(10). Accessed February 27, 2009. < Back to Top >
Cancer PainAdverse effects of transdermal opiates treating moderate-severe cancer pain in comparison to long-acting morphine: a meta-analysis and systematic review of the literature Tassinari D, Sartori S, Tamburini E, et al. J Palliat Med. 2008(Apr);11(3):492-501. Accessed February 27, 2009. See abstract...> Methadone for cancer pain Nicholson AB. Cochrane Database. 2007,4. Accessed August 24, 2009. See abstract...> Oral morphine for cancer pain Wiffen PJ, McQuay HJ. Cochrane Database. 2007,4. Accessed August 24, 2009. Biphosphonates for advanced prostate cancer Yuen KK, Shelley M, Sze WM, et al. Cochrane Database. 2006,4. Accessed August 24, 2009. See abstract...> Calcitonin for metastatic bone pain Martinez MJ, Roqué i Figuls M, Alonso Coello P, et al. Cochrane Database. 2006,3. Accessed August 24, 2009. See abstract...> Controlled clinical trials in cancer pain. How controlled should they be? A qualitative systematic review Bell RF, Wisloff T, Eccleston C, et al. Br J Cancer. 2006(Jun);94(11):1559-1567. Accessed February 27, 2009. See abstract...> Opioids for the management of breakthrough (episodic) pain in cancer patients Zeppetella G, Ribeiro MDC. Cochrane Database. 2006,1. Accessed August 24, 2009. See abstract...> Comparative efficacy of epidural, subarachnoid and intracerebroventricular opioids in patients with pain due to cancer Ballantyne JC, Carwood CM. Cochrane Database. 2005,2. Accessed August 24, 2009. See abstract...> NSAIDS or paracetamol, alone or combined with opioids, for cancer pain McNicol E, Strassels SA, Goudas L, et al. Cochrane Database. 2005,2. Accessed August 24, 2009. Radioisotopes for metastatic bone pain Roqué i Figuls M, Martinez MJ, Alonso-Coello Pl. Cochrane Database. 2003,4. Accessed August 24, 2009. See abstract...> < Back to Top >
Cardiac & Chest PainChinese herbal medicine suxiao jiuxin wan for angina pectoris Duan X, Zhou L, Wu T, et al. Cochrane Database. 2008,1. Accessed August 24, 2009. See abstract...> Tongxinluo (Tong xin luo or Tong-xin-luo) capsule for unstable angina pectoris Wu T, Harrison RA, Chen X, et al. Cochrane Database. 2006,4. Accessed August 24, 2009. See abstract...> Psychological interventions for symptomatic management of non-specific chest pain in patients with normal coronary anatomy Kisely S, Campbell LA, Skerritt P. Cochrane Database. 2005,1. Accessed August 24, 2009. See abstract...> < Back to Top >
Chronic & Intractable PainMultidisciplinary treatment for chronic pain: a systematic review of interventions and outcomes Scascighini L, Toma V, Dober-Spielmann S, et al. Rheumatology. 2008(May);47(5):670-678. Accessed February 27, 2009. See abstract...> Long-term opioid therapy for chronic noncancer pain: a systematic review and meta-analysis of efficacy and safety Noble M, Tregear SJ, Treadwell JR, et al. J Pain Symptom Manage. 2008(Feb);35(2):214-228. Accessed February 27, 2009. See abstract...> Management of chronic prostatitis/chronic pelvic pain syndrome: an evidence-based approach Dimitrakov JD, Kaplan SA, Kroenke K, et al. Urology. 2006(May);67(5):881-888. Accessed February 27, 2009. See abstract...> Pain management for sickle cell disease in children and adults Dunlop RJ, Bennett KC. Cochrane Database. 2006, 2. Accessed August 24, 2009. See abstract...> Local anesthetic sympathetic blockade for complex regional pain syndrome Cepeda MS, Carr DB, Lau J. Cochrane Database. 2005,4. Accessed August 24, 2009. See abstract...> Spinal cord stimulation for chronic pain Mailis-Gagnon A, Furlan AD, Sandoval JA, et al. Cochrane Database. 2004,3. Accessed August 24, 2009. See abstract...> < Back to Top >
Geriatric PainMind-body interventions for chronic pain in older adults: a structured review Morone NE, Greco CM. Pain Medicine. 2007(May-Jun);8(4):359-375. Accessed February 27, 2009. See abstract...> < Back to Top >
Gynecological or Obstetrical PainAcupuncture for pelvic and back pain in pregnancy: a systematic review Ee CC, Manheimer E, Pirotta MV, et al. Am J Obstet Gynecol. 2008(Mar);198(3):254-259. Accessed February 27, 2009. See abstract...> Complementary and alternative therapies for pain management in labour Smith CA, Collins CT, Cyna AM, et al. Cochrane Database. 2006,4. Accessed August 24, 2009. See abstract...> Non-steroidal anti-inflammatory drugs for heavy bleeding or pain associated with intrauterine-device use Grimes DA, Hubacher D, Lopez LM, et al. Cochrane Database. 2006,4. Accessed August 24, 2009. Guidelines for the management of pelvic pain associated with endometriosis: a systematic appraisal of their quality Appleyard TL, Mann CH, Khan KS. BJOG: An International Journal of Obstetrics and Gynaecology. 2006(Jul);113(7):749-757. Accessed February 27, 2009. See abstract...> Spinal manipulation for primary and secondary dysmenorrhoea Proctor ML, Hing W, Johnson TC, et al. Cochrane Database. 2006,3. Accessed August 24, 2009. See abstract...> Non-steroidal anti-inflammatory drugs for pain in women with endometriosis Allen C, Hopewell S, Prentice A, et al. Cochrane Database. 2009,2. Accessed August 24, 2009. See abstract...> Musculoskeletal causes of chronic pelvic pain: a systematic review of existing therapies: Part II Tu FF, As-Sanie S, Steege JF. Obstet Gynecol Surv. 2005(Jul);60(7):474-483. Accessed February 27, 2009. Interventions for treating chronic pelvic pain in women Stones W, Cheong YC, Howard FM. Cochrane Database. 2005,2. Accessed August 24, 2009. See abstract...> Topically applied anaesthetics for treating perineal pain after childbirth Hedayati H, Parsons J, Crowther CA. Cochrane Database. 2005,2. Accessed August 24, 2009. See abstract...> Musculoskeletal causes of chronic pelvic pain: a systematic review of diagnosis: Part I Tu FF, Sawsan AS , Steege JF. Obstet Gynecol Surv. 2005(Jun);60(6):379-385. Accessed February 27, 2009. < Back to Top >
HeadacheAnticonvulsants in migraine prophylaxis: a Cochrane review Mulleners WM, Chronicle EP. Cephalalgia. 2008(Jun);28(6):585-597. Accessed February 27, 2009. See abstract...> Acute treatment and prevention of menstrually-related migraine headache: evidence-based review Pringsheim T, Davenport WJ, Dodick D. Neurology. 2008(Apr);70(17):1555-1563. Accessed February 27, 2009. See abstract...> A review of evidence-based medicine and meta-analytic reviews in migraine Tfelt-Hansen P. Cephalalgia. 2006(Nov);26(11):1265-1274. Accessed February 27, 2009. See abstract...> The influence of estrogen on migraine: a systematic review Brandes JL. JAMA. 2006(Apr);295(15):1824-1830. Accessed February 27, 2009. See abstract...> An otolaryngology, neurology, allergy, and primary care consensus on diagnosis and treatment of sinus headache Levine HL, Setzen M, Cady RK, et al. Otolaryngol Head Neck Surg. 2006(Mar);134(3):516-523. Accessed February 27, 2009. See abstract...> Addendum to assessment: Prevention of post-lumbar puncture headaches. Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology Armon C, Evans RW. 2005(Aug);65(4):510-512. Accessed February 27, 2009. See text PDF...> Selective serotonin re-uptake inhibitors (SSRIs) for preventing migraine and tension-type headaches Moja PL , Cusi C, Sterzi RR, et al. Cochrane Database. 2005,3. Accessed February 27, 2009. See abstract...> Non-invasive physical treatments for chronic/recurrent headache Bronfort G, Nilsson N, Haas M, et al. Cochrane Database. 2004,3. Accessed August 24, 2009. See abstract...> Inpatient treatment of headache: an evidence-based assessment Freitag FG, Lake A 3rd, Lipton R, et al. Headache. 2004(Apr);44(4):342-360. Accessed February 27, 2009. See reference & summary...> Oral sumatriptan for acute migraine McCrory DC , Gray RN. Cochrane Database. 2003,3. Accessed August 24, 2009. See abstract...> Assessment: prevention of post-lumbar puncture headaches. Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology Evans RW, Armon C, Frohman EM, et al. Neurology. 2000(Oct);55(7):909-914. See text PDF...> A 2005 addendum to this assessment evaluated a study reporting high level evidence on the use of atraumatic needles in diagnostic lumbar punctures. Neurology. 2005;65:510-512. Accessed February 27, 2009. < Back to Top >
Musculoskeletal Pain (including Arthritis and Fibromyalgia)
Leite FMG, Atallah ÁN, El Dib R, et al. Cochrane Database. 2009, 3. According to very limited evidence (2 small studies), the use of cyclobenzaprine for myofascial pain cannot be recommended. Further high quality RCTs are needed before firm conclusions on the effectiveness and safety of cyclobenzaprine for this condition can be made. Accessed July 11, 2009. See abstract…> Exercise for intermittent claudication [leg muscle pain due to insufficient blood flow] Watson L, Ellis B, Leng GC. Cochrane Database. 2008,4. A systematic review on the effectiveness of treatment with antidepressants in fibromyalgia syndrome Uceyler N, Hauser W, Sommer C. Arthritis Rheum. 2008(Sep 15);59(9):1279-1298. Doctors' attitudes and beliefs regarding acute low back pain management: a systematic review Fullen BM, Baxter GD, O’Donovan BG, et al. Pain. 2008(Jun);136(3):388-396. Accessed February 27, 2009. See abstract...> Exercise for fibromyalgia: a systematic review Busch AJ, Schachter CL, Overend TJ, et al. J Rheumatology. 2008(Jun);35(6):1130-1144. Accessed February 27, 2009. See abstract...> Naftidrofuryl for intermittent claudication [for symptoms of muscle pain with exercise] De Backer TLM, Vander Stichele R, Lehert P, et al. Cochrane Database. 2008,2. Accessed August 24, 2009. See abstract...> The basis for recommending repeating epidural steroid injections for radicular low back pain: a literature review Novak S, Nemeth WC. Arch Phys Med Rehabil. 2008(Mar);89(3):543-552. Accessed February 27, 2009. See abstract...> Antidepressants for non-specific low back pain Urquhart DM, Hoving JL, Assendelft WW, et al. Cochrane Database. 2008,1. Accessed August 24, 2009. See abstract...> Prolotherapy injections for chronic low-back pain Dagenais S, Yelland MJ , Del Mar C, et al. Cochrane Database. 2007,2. Accessed August 24, 2009. Traction for low-back pain with or without sciatica Clarke JA, van Tulder MW, Blomberg SEI, et al. Cochrane Database. 2007,2. Accessed August 24, 2009. See abstract...> Systematic review: opioid treatment for chronic back pain: prevalence, efficacy, and association with addiction Martell BA, O’Connor PG, Kerns RD, et al. Ann Intern Med. 2007(Jan);146(2):116-127. Accessed February 27, 2009. See abstract...> Fear avoidance and prognosis in back pain: a systematic review and synthesis of current evidence Pincus T, Vogel S, Burton AK, et al. Arthritis Rheum. 2006(Dec);54(12):3999-4010. Accessed February 27, 2009. See abstract...> The comparative efficacy and safety of biologics for the treatment of rheumatoid arthritis: a systematic review and metaanalysis Gartlehner G, Hansen RA, Jonas BL, et al. J Rheumatology. 2006(Dec);33(12):2398-2408. Accessed February 27, 2009. See abstract...> A systematic review of the effectiveness of adalimumab, etanercept and infliximab for the treatment of rheumatoid arthritis in adults and an economic evaluation of their cost-effectiveness Chen YF, Jobanputra P, Barton P, et al. Health Technol Assess. 2006(Nov);10(42):1-248. (Note: costs are represented in British pounds.) Accessed February 27, 2009. See web link to order full-text...> Effectiveness of interventions for the treatment of acute and prevention of recurrent gout—a systematic review Sutaria S, Katbamna R, Underwood M. Rheumatology. 2006(Nov);45(11):1422-1431. Accessed February 27, 2009. See abstract...> Oral steroids for adhesive capsulitis Buchbinder R, Green S, Youd JM, et al. Cochrane Database. 2006,4. Accessed August 24, 2009. See abstract...> Inconsistent grading of evidence across countries: a review of low back pain guidelines Murphy AY, van Teijlingen ER, Gobbi MO. J Manipulative Physiol Ther. 2006(Sep);29(7):576-581. Accessed February 27, 2009. See text PDF...> Interventions for the prevention and management of neck/upper extremity musculoskeletal conditions: A systematic review Boocock MG, McNair PJ, Larmer PJ, et al. Occup Environ Med. 2006(Sep);45(11):1422-1431. Accessed February 27, 2009. See abstract...> Osteoarthritis of the knee and hip and activity: a systematic international review and synthesis (OASIS) Vignon E, Valat JP, Rossignol M, et al. Joint Bone Spine. 2006(Jul);73(4):442-455. Accessed February 27, 2009. See abstract...> A critical review of guidelines for low back pain treatment Arnau JM, Vallano A, Lopez A, et al. European Spine J. 2006(May);15(5):543-553. Accessed February 27, 2009. See abstract...> Herbal medicine for low back pain Gagnier JJ, van Tulder M, Berman B, et al. Cochrane Database. 2006,2. Accessed August 24, 2009. Intraarticular corticosteroid for treatment of osteoarthritis of the knee Bellamy N, Campbell J, Welch V, et al. Cochrane Database. 2006,2. Accessed August 24, 2009. See abstract...> Viscosupplementation for the treatment of osteoarthritis of the knee Bellamy N, Campbell J, Welch V, et al. Cochrane Database. 2006,2. Accessed August 24, 2009. Outcome of non-invasive treatment modalities on back pain: an evidence-based review Van Tulder MW, Koes B, Malmivaara A. European Spine J. 2006(Jan);15(Suppl. 1):S64-S81. Accessed February 27, 2009. See abstract...> Superficial heat or cold for low back pain French SD, Cameron M, Walker BF, et al. Cochrane Database. 2006,1. Accessed August 24, 2009. Shock wave therapy for lateral elbow pain Buchbinder R, Green SE, Youd JM, et al. Cochrane Database. 2005,4. Accessed August 24, 2009. Exercise therapy for treatment of non-specific low back pain Hayden JA, van Tulder MW, Malmivaara A, et al. Cochrane Database. 2005,3. Accessed August 24, 2009. See abstract...> Exercises for mechanical neck disorders Kay TM, Gross A, Goldsmith C, et al. Cochrane Database. 2005,3. Accessed August 24, 2009. See abstract...> Transcutaneous electrical nerve stimulation (TENS) versus placebo for chronic low-back pain Khadilkar A, Odebiyi D, Brosseau L, et al. Cochrane Database. 2008,4. Accessed August 24, 2009. See abstract...> Systematic review of the literature of low-level laser therapy (LLT) in the management of neck pain Chow RT, Barnsley L. Lasers Surg Med. 2005(Jul);37(1):46-52. Accessed February 27, 2009. See abstract...> Acupuncture for shoulder pain Green S, Buchbinder R, Hetrick S. Cochrane Database. 2005,2. Accessed August 24, 2009. See abstract...> Acupuncture and dry-needling for low back pain Furlan AD, van Tulder MW, Cherkin DC , et al. Cochrane Database. 2005,1. Accessed August 24, 2009. See abstract...> Management of fibromyalgia syndrome Goldenberg DL, Burckhardt C, Crofford L. JAMA. 2004(Nov);292(19):2388-2395. Accessed February 27, 2009. See abstract...> Bed rest for acute low-back pain and sciatica Hagen KB, Hilde G, Jamtvedt G, et al. Cochrane Database. 2004,4. Accessed August 24, 2009. See abstract...> Comparative efficacy and safety of skeletal muscle relaxants for spasticity and musculoskeletal conditions: a systematic review Chou R, Peterson K, Helfand M. J Pain Symptom Manage. 2004(Aug);28(2):140-175. Accessed February 27, 2009. See text PDF...> Spinal manipulative therapy for low-back pain Assendelft WJJ, Morton SC, Yu EI, et al. Cochrane Database. 2004,1. Accessed August 24, 2009. Acute low back pain: systematic review of its prognosis Pengel LHM, Herbert RD, Maher CG, et al. BMJ. 2003(Aug);327(323):1-5. Accessed February 27, 2009. See text...> Multidisciplinary biopsychosocial rehabilitation for neck and shoulder pain among working age adults Karjalainen K, Malmivaara A, van Tulder M, et al. Cochrane Database. 2003,2. Accessed August 24, 2009. See abstract...> Multidisciplinary biopsychosocial rehabilitation for subacute low-back pain among working age adults Karjalainen K, Malmivaara A, van Tulder M, et al. Cochrane Database. 2003,2. Accessed August 24, 2009. See abstract...> Physiotherapy interventions for shoulder pain Green S, Buchbinder R, Hetrick S. Cochrane Database. 2003,2. Accessed August 24, 2009. See abstract...> Corticosteroid injections for shoulder pain Buchbinder R, Green S, Youd JM. Cochrane Database. 2003,1. Accessed August 24, 2009. See abstract...> Radiofrequency denervation for neck and back pain Niemisto L, Kalso E, Malmivaara A, et al. Cochrane Database. 2003,1. Accessed August 24, 2009. Massage for low-back pain Furlan AD, Imamura M, Dryden T, et al. Cochrane Database. 2008,4. Accessed August 24, 2009. < Back to Top >
Neurological/Neuropathic PainSurgical versus non-surgical treatment for carpal tunnel syndrome Verdugo RJ, Salinas RA, Castillo JL, Cea JG. Cochrane Database. 2008,4. Pain associated with multiple sclerosis: systematic review and proposed classification O’Connor AB, Schwid SR, Herrmann DN, et al. Pain. 2008(Jun 30);137(1):96-111. Corticosteroids for preventing postherpetic neuralgia He L, Zhang D, Zhou M, et al. Cochrane Database. 2008,1. Accessed August 24, 2009. See abstract...> Antidepressants for neuropathic pain Saarto T, Wiffen PJ. Cochrane Database. 2007,4. Accessed August 24, 2009. See abstract...> Effects of treatments for symptoms of painful diabetic neuropathy: systematic review Wong MC, Chung JW, Wong TK. BMJ. 2007(Jul);335(7610);Online First, 10 pages. Accessed February 27, 2009. See abstract...> Topical lidocaine for the treatment of postherpetic neuralgia Khaliq W, Alam S, Puri NK. Cochrane Database. 2007,2. Accessed August 24, 2009. See abstract...> Pain after spinal cord injury: an evidence-based review for clinical practice and research. Report of the National Institute on Disability and Rehabilitation Research Spinal Cord Injury Measures meeting Bryce TN, Budh CN, Cardenas DD, et al. J Spinal Cord Med. 2007;30(5):421-440. Accessed February 27, 2009. See text PDF...> Non-antiepileptic drugs for trigeminal neuralgia He L, Wu B, Zhou M, et al. Cochrane Database. 2006,3. Accessed August 24, 2009. See abstract...> Opioids for neuropathic pain Eisenberg E, McNicol E, Carr DB. Cochrane Database. 2006,3. Accessed August 24, 2009. See abstract...> Tramadol for neuropathic pain Hollingshead J, Dühmke RM, Cornblath DR. Cochrane Database. 2006,3. Accessed August 24, 2009. See abstract...> Practice advisory: utility of surgical decompression for treatment of diabetic neuropathy. Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology Chaudhry V, Stevens JC, Kincaid J, et al. Neurology. 2006(Jun);66(12):1805-1808. Accessed February 27, 2009. See text PDF...> Systemic administration of local anesthetic agents to relieve neuropathic pain Challapalli V, Tremont-Lukats IW, McNicol ED, et al. Cochrane Database. 2005,4. Accessed August 24, 2009. See abstract...> Drug therapy for chronic idiopathic axonal polyneuropathy Vrancken AFJE, van Schaik IN, Hughes RAC, et al. Cochrane Database. 2004,2. Accessed August 24, 2009. See abstract...> < Back to Top >
Non-Opioid & Complementary Therapies ...also see Non-Opioid Therapies tab sectionExercise therapy and orthotic devices in rheumatoid arthritis: evidence-based review Oldfield V, Felson DT. Curr Opin Rheumatol. 2008(May);20(3):353-359. Accessed February 27, 2009. Hypnotherapy for treatment of irritable bowel syndrome Webb AN, Kukuruzovic RH, Catto-Smith AG, et al. Cochrane Database. 2007,4. Accessed August 24, 2009. See abstract...> Efficacy of complementary and alternative medicine therapies in relieving cancer pain: a systematic review Bardia A, Barton DL, Prokop LJ, et al. J Clin Oncol. 2006(Dec);24(34):5457-5464. Accessed February 27, 2009. See abstract...> Acupuncture for neck disorders Trinh K, Graham N, Gross A, et al. Cochrane Database. 2006,3. Accessed August 24, 2009. See abstract...> Spinal cord stimulation for complex regional pain syndrome: a systematic review of the clinical and cost-effectiveness literature and assessment of prognostic factors Taylor RS, Van Buyten JP, Buchser E. Eur J Pain. 2006(Feb);10(2):91-101. Accessed February 27, 2009. See abstract...> Trunk-strengthening exercises for chronic low back pain: a systematic review Slade SC, Ther MM, Keating JL. J Manipulative Physiol Ther. 2006(Feb);29(2):163-173. Accessed February 27, 2009. See abstract...> Anticonvulsant drugs for acute and chronic pain Wiffen PJ, Collins S, McQuay HJ, et al. Cochrane Database. 2005,3. Accessed August 24, 2009. See abstract...> Carbamazepine for acute and chronic pain in adults Wiffen PJ, McQuay HJ, Moore RA. Cochrane Database. 2005,3. Accessed August 24, 2009. See abstract...> Gabapentin for acute and chronic pain Wiffen PJ, McQuay HJ, Rees J, et al. Cochrane Database. 2005,3. Accessed August 24, 2009. Psychological interventions for symptomatic management of non-specific chest pain in patients with normal coronary anatomy Kisely S, Campbell LA , Skerritt P. Cochrane Database. 2005,1. Accessed August 24, 2009. See abstract...> Non-invasive physical treatments for chronic/recurrent headache Bronfort G, Nilsson N, Haas M, et al. Cochrane Database. 2004,3. Accessed August 24, 2009. See abstract...> Tai chi for treating rheumatoid arthritis Han A, Judd MG, Welch V, et al. Cochrane Database. 2004,3. Accessed August 24, 2009. See abstract...> Stabilisation splint therapy for temporomandibular pain dysfunction syndrome Al-Ani MZ, Davies SJ, Gray RJM, et al. Cochrane Database. 2004,1. Accessed August 24, 2009. See abstract...> Topical agents or dressings for pain in venous leg ulcers Briggs M, Nelson EA. Cochrane Database. 2003,1. Accessed August 24, 2009. See abstract...> Psychological therapies for sickle cell disease and pain Anie KA, Green J. Cochrane Database. 2002,2. Accessed August 24, 2009. See abstract...> < Back to Top >
Opioid Therapy & Safety ...also see Opioid Rx tab sectionPeripherally acting opioid antagonists in the treatment of opiate-related constipation: a systematic review Becker G, Galandi D, Blum HE. J Pain Symptom Manage. 2007(Nov);34(5):547-565. Accessed February 27, 2009. See abstract...> Methadone for cancer pain Nicholson AB. Cochrane Database. 2007,4. Accessed August 24, 2009. See abstract...> Oral morphine for cancer pain Wiffen PJ, McQuay HJ. Cochrane Database. 2007,4. Accessed August 24, 2009. See abstract...> Systematic review: opioid treatment for chronic back pain: prevalence, efficacy, and association with addiction Martell BA, O’Connor PG, Kerns RD, et al. Ann Intern Med. 2007(Jan);146(2):116-127. Accessed February 27, 2009. See text PDF...> Patient controlled opioid analgesia versus conventional opioid analgesia for postoperative pain Hudcova J, McNicol E, Quah C, et al. Cochrane Database. 2006,4. Accessed August 24, 2009. See abstract...> Epidural pain relief versus systemic opioid-based pain relief for abdominal aortic surgery Nishimori M, Ballantyne JC, Low JHS. Cochrane Database. 2006,3. Accessed August 24, 2009. See abstract...> Opioids for neuropathic pain Eisenberg E, McNicol E, Carr DB. Cochrane Database. 2006,3. Accessed August 24, 2009. See abstract...> Opioid switching: a systematic and critical review Mercadante S, Bruera E. Cancer Treat Rev. 2006(Jun);32(4):304-315. Accessed February 27, 2009. Opioid-induced hyperalgesia – a qualitative systematic review Angst MS, Clark JD. Anesthesiology. 2006(Mar);104(3):570-587. Accessed February 27, 2009. See abstract...> Opioids for the management of breakthrough (episodic) pain in cancer patients Zeppetella G, Ribeiro MDC. Cochrane Database. 2006,1. Accessed August 24, 2009. See abstract...> Patient controlled intravenous opioid analgesia versus continuous epidural analgesia for pain after intra-abdominal surgery Werawatganon T, Charuluxanun S. Cochrane Database. 2005,1. Accessed August 24, 2009. See abstract...> Opioid switching to improve pain relief and drug tolerability Quigley C. Cochrane Database. 2004,3. Accessed August 24, 2009. See abstract...> < Back to Top >
Pain In Palliative CareEvidence for improving palliative care at the end of life: a systematic review [includes pain management] Lorenz KA, Lynn J, Dy SM, et al. Ann Intern Med. 2008(Jan);148(2):147-159. Accessed February 27, 2009. See abstract...> Laxatives for the management of constipation in palliative care patients Miles CL, Fellowes D, Goodman ML, et al. Cochrane Database. 2006,4. Accessed August 24, 2009. Palliation of metastatic bone pain Sze WM, Shelley M, Held I, et al. Cochrane Database. 2002,1. Accessed August 24, 2009. See abstract...> < Back to Top >
Pediatric PainTreatment of children with migraine in the emergency department: a qualitative systematic review Bailey B, McManus BC. Pediatr Emerg Care. 2008(May);24(5):321-330. Accessed February 27, 2009. A systematic review of randomized controlled trials examining psychological interventions for needle-related procedural pain and distress in children and adolescents: an abbreviated Cochrane Review Uman LS, Chambers CT, McGrath PJ, et al. J Pediatr Psychol. 2008(Apr); Early online publication prior to print. Accessed February 27, 2009. See abstract...> Music for pain and anxiety in children undergoing medical procedures: a systematic review of randomized controlled trials Klassen JA, Liang Y, Tjosvold L, et al. Ambul Pediatr. 2008(Mar-Apr);8(2)117-128. Accessed February 27, 2009. See abstract...> Review of systematic reviews on acute procedural pain in children in the hospital setting Stinson J, Yamada J, Dickson A, et al. Pain Res Manag. 2008(Jan-Feb);13(1):51-57. Accessed February 27, 2009. See abstract...> Dietary interventions for recurrent abdominal pain (RAP) and irritable bowel syndrome (IBS) in childhood Huertas-Ceballos A, Logan S, Bennett C, et al. Cochrane Database. 2009,1. Accessed August 24, 2009. See abstract...> Psychosocial interventions for recurrent abdominal pain (RAP) and irritable bowel syndrome (IBS) in childhood Huertas-Ceballos A, Logan S, Bennett C, et al. Cochrane Database. 2008,1. Accessed August 24, 2009. See abstract...> A qualitative systematic review of morphine treatment in children with postoperative pain Duedahl TH, Hansen EH. Paediatr Anaesth. 2007(Aug);17(8):756-774. Accessed February 27, 2009. See abstract...> Repeated supratherapeutic doses of paracetamol in children – a literature review and suggested clinical approach Kozer E, Greenberg R, Zimmerman DR, et al. Acta Paediatr. 2006(Oct);95(10):1165-1171. Accessed February 27, 2009. See abstract...> Psychological interventions for needle-related procedural pain and distress in children and adolescents Uman LS, Chambers CT , McGrath PJ, et al. Cochrane Database. 2006,4. Accessed August 24, 2009. The effectiveness of complementary therapies on the pain experience of hospitalized children Lassetter JH. J Holist Nurs. 2006(Sep);24(3):196-208. Accessed February 27, 2009. See abstract...> Breastfeeding or breast milk for procedural pain in neonates Shah PS, Aliwalas LL, Shah V. Cochrane Database. 2006,3. Accessed August 24, 2009. See abstract...> Conservative treatments of children with episodic tension-type headache. A systematic review Verhagen AP, Damen L, Berger MY, et al. J Neurol. 2005(Oct);252(10):1147-1154. Accessed February 27, 2009. See abstract...> Symptomatic treatment of migraine in children: a systematic review of medication trials Damen L, Bruijn JK, Verhagen AP, et al. Pediatrics. 2005(Aug);116(2):e295-302. Accessed February 27, 2009. See text PDF...> Chronic abdominal pain in children American Academy of Pediatrics. Pediatrics. 2005(Mar);115(3):e370-e381. Accessed February 27, 2009. See text PDF...> Pain relief for neonatal circumcision Brady-Fryer B, Wiebe N, Lander JA. Cochrane Database. 2004,3. Accessed August 24, 2009. See abstract...> Caudal epidural block versus other methods of postoperative pain relief for circumcision in boys Cyna AM, Middleton P. Cochrane Database. 2008,4. Accessed August 24, 2009. See abstract...> Psychological therapies for the management of chronic and recurrent pain in children and adolescents Eccleston C, Palermo TM, Williams et al. Cochrane Database. 2009,2. Accessed August 24, 2009.
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Perioperative PainSingle dose oral lumiracoxib for postoperative pain Roy YM, Derry S, Moore RA. Cochrane Database. 2007,4. Accessed August 24, 2009. See abstract...> Gabapentin and postoperative pain--a systematic review of randomized controlled trials Ho KY, Gan TJ, Habib AS. Pain. 2006(Dec);126(1-3):91-101. Accessed February 27, 2009. See abstract...> Patient controlled opioid analgesia versus conventional opioid analgesia for postoperative pain Hudcova J, McNicol E, Quah C, et al. Cochrane Database. 2006,4. Accessed August 24, 2009. See abstract...> EMLA and Amethocaine for reduction of children’s pain associated with needle insertion Lander JA, Weltman BJ, So SS. Cochrane Database. 2006,3. Accessed August 24, 2009. See abstract...> Epidural pain relief versus systemic opioid-based pain relief for abdominal aortic surgery Nishimori M, Ballantyne JC, Low JHS. Cochrane Database. 2006,3. Accessed August 24, 2009. See abstract...> The role of COX-2 inhibitors in the perioperative setting: efficacy and safety—a systematic review Zemmel MH. AANA Journal. 2006(Feb);74(1):49-60. Accessed February 27, 2009. See text PDF...> A qualitative systematic review of peri-operative dextromethorphan in post-operative pain Duedahl TH, Romsing J, Moiniche S, et al. Acta Anaesthesiol Scand. 2006(Jan);50(1):1-13. Accessed February 27, 2009. See abstract...> Perioperative ketamine for acute postoperative pain Bell RF, Dahl JB, Moore RA et al. Cochrane Database. 2006,1. Accessed August 24, 2009. See abstract...> Patient controlled intravenous opioid analgesia versus continuous epidural analgesia for pain after intra-abdominal surgery Werawatganon T, Charuluxanun S. Cochrane Database. 2005,1. Accessed August 24, 2009. See abstract...> Single dose oral indometacin for the treatment of acute postoperative pain Moore RA, Derry S, Mason L, et al. Cochrane Database. 2004,4. Accessed August 24, 2009. See abstract...> Single dose oral naproxen and naproxen sodium for acute postoperative pain in adults Derry C, Derry S, Moore RA, et al. Cochrane Database. 2009,1. Accessed August 24, 2009. See abstract...> Single dose oral diclofenac for acute postoperative pain in adults Derry P, Derry S, Moore RA, et al. Cochrane Database. 2009,2. Accessed August 24, 2009. See abstract...> Single dose oral paracetamol (acetaminophen) for postoperative pain in adults Toms L, McQuay HJ, Derry S, et al. Cochrane Database. 2008,4. Accessed August 24, 2009. See abstract...> Epidural analgesia for pain relief following hip or knee replacement Choi PT, Bhandari M, Scott J, et al. Cochrane Database. 2003,3. Accessed August 24, 2009. See abstract...> < Back to Top >
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The following Systematic Reviews are organized in logical clinical categories, beginning with the most recently published, updated, or reviewed paper in each category. Links are provided to the complete reference (and abstract in some cases), or the full-text of the review when available.
Most items listed on this page are from sources not in accord with the Pain Treatment Topics 
= entry added or changed during latest update. 